Do you ever wonder how doctor chooses an appropriate medication for your family? Do you feel overwhelmed from the sheer number of available medications? These tips will help realize the choices that can be found. In subsequent articles, there will become more information about each class of treatment method. healthjade
While there are hundreds of medications and combinations of medications available, undoubtedly are a seven different classes of medication. Each class works differently. Your physician uses his knowledge about you as well as your specific type of diabetes to picking out if you need any medication, and when so, which class to use. Precisely what chooses a medication from that grade. If you require medication from more than one class he might want to prescribe more than a single medication or a compounding pill which has two or more medications contained involved with it. This article will gives a brief overview on the classes of medications and how they work.
1.) The oldest class of medication is the sulfonylureas. Until the mid-1990s, this was the only class of oral medications available. Your body must be able to produce insulin being able to for these to get beneficial, as they work by stimulating the beta cells of the pancreas to secrete blood insulin. Some examples of the first generation of these medications are: Tolbutamide (orinase), Tolinase (tolazamide), and Diabinese (chlorpropamide). Some of self-assured generation medications are: Glipizide (glucatrol), extended release Glipizide (glucatrol XL), Glyburide (Micronase, Diabeta), Glynase (micronized glyburide), and Glimepiride. These medications are distinguished by how long they last your past body, and whether or not are cleared the actual kidney or the liver. There are two other drugs in this class: Prandin and Starlix, which can supply before meals purely because they last for the most short time.
2.) The biguanide class has only 1 medication, called Metformin. Other names are Fortamet, Glucophage, Gluymetza, and Riomet. Prescription drugs works by decreasing glucose production previously liver, and in addition, it causes a small increase in glucose uptake by skeletal muscle. If there isn’t any contraindications, the American Diabetes Association and also the American college of clinical endocrinologists recommends using this medication first.
3.) In the mid-1990s, the Thiazolidinedione class of medications (also known as glitizones or TZDs) was developed. Their primary mechanism of action is strengthen insulin sensitivity, which results in more glucose being taken up by skeletal muscle. Three medications were developed. The first, Rezulin (troglitazone), was become increasingly popular the market because it was suggested to cause liver problems. The second, Avandia (rosiglitazone), was withdrawn by the market in Europe but was allowed under selling restrictions in the US because of an increase in cardiovascular events. 3rd workout medication, Actos (pioglitazone) had sales suspended in France and Germany because a study suggested it might increase the risk of bladder cancer.
4.) Drugs which affect the incretin system are divided into two subclasses:
a. The first division is composed of injectable drugs which mimic the effect of natural incretins produced by cups of water. Medications in this class include Byetta (exenetide), Bydureon (long acting exenatide) Victoza (liraglutide), and Symlin. They work by increasing insulin secretion in response to glucose (sugar), reducing the rate at which the liver puts out glucose, decreasing appetite, and by slowing the rate the stomach empties. These medications have become quite popular since these can help with weight loss, that has an extremely low incidence of hypoglycemia. However, these medications have been in news reports because they in order to associated with pancreatitis, and may lead to a slight increase in medullary thyroid cancers.
b. The medications in this class work by blocking the enzyme which breaks down the incretins. While the level of natural incretins increases somewhat, these drugs are not as effective as the injectable ones. Medications in this particular class include Januvia (sitagliptin), Onglyza (saxagliptin), and Tradjenta. These kind of are being observed to look for complications similar for the injectable medications. They very rarely cause hypoglycemia and don’t cause weight add on. They are all being evaluated to order potential cancer jeopardy.
5.) There are three Alpha Glucosidase Inhibitors: Acarbose (Precose), Miglitol (Glyset), and Voglibose. These work by preventing digestion of carbohydrates the actual intestine. By preventing carbohydrates from being converted into simple sugars and distributed around the blood stream from the intestine, this class of medications can help to keep the blood sugar from rising after meals.
6.) The newest class of medications is the SGLT2 inhibitors, which block absorption of glucose by the elimination. By increasing the amount of glucose lost through the urine, and lowering the amount of sugar absorbed back in the blood stream, blood sugar may be diminished. Because none of these medications already been approved by the FDA, the names of the medications are omitted from this article.
7.) Insulin should be used for people with type I Diabetes and is often needed for individuals with type 2 High blood pressure. There are many types and delivery systems which will be discussed subsequently.
With a thorough understanding of your type of diabetes, your physician can wade through all the options to decide on the best match an individual. More detailed information about each drug class will be presented in subsequent articles here, and in my website, diabeticsurvivalkit.com. Please feel free to visit at that whenever for information about medications, cooking videos featuring diabetic meal and dessert recipes, and current news articles.